Thanks guys and girls ;) I must admit its too bad that they don't make sci-fi like Farscape any more maybe someday, at least i had a good excuse to watch it all over again :D.
As for Z-brush i did try it somewhere in middle of the project because sculpting on higher levels is still a bit choppy in modo especially switching between SDS levels or maybe i threw too much polys at it ;), any way i didn't get too far in Zbrush too due to annoying interface, especially navigation in viewport, and since i've done most of the work already in Modo i said to my self if could start it in Modo then you could/should finish it in Modo too, besides i didn't had time to learn new tools and workflow.
Im definitely gonna try out Zbrush in my spare time but if it comes to buying it i'll wait for Zbrush 5 with 64bit support.
Unfortunately i had to deal with symmetry issue too, my workaround was to sculpt to certain point then retopology (it helps to reduce poly count as well), mirror it and so on until i reach a point when i've started to sculpt wrinkles and all the small details but in that case its better to work without symmetry to avoid unnatural symmetrical look.